Calcium channel blockers, also called ‘calcium antagonists’, calcium channel blockers inhibit the transfer of calcium into cardiac and vascular muscle cells. They are particularly indicated in the management of hypertension.
How do they work?
On average duration of action of 24 hours, calcium channel blockers block the entry of calcium into muscle cells of arteries. They are at the origin of arterial relaxation, while between these vessels less resistance to blood flow. This is what specialists call vasodilation. Blood pressure decreases. Calcium antagonists are also indicated in the management of angina, or angina.
The cons-indications and precautions
The side effects of these drugs are related to their vasodilatory effects: lower limb edema, headache, redness of the face … Generally, they disappear within weeks.