– Levodopa (L-dopa) is the drug most commonly used antiparkinsonian. It turns into dopamine synthesis in the body of the patient. However, it causes many complications in the central nervous system: motor fluctuations, involuntary movements and drowsiness.
– The dopamine agonists act directly on the receptors of the latter. Administered in combination with L-dopa, these synthetic molecules mimic the action of dopamine.
– Inhibitors of MAO-B (monoamine oxidase B) limit the degradation of dopamine.
– Inhibitors of catechol-O-methyltransferase (COMT) have the same effect as inhibitors of MAO-B. They can therefore enhance the efficacy of dopamine.
– The anticholinergic drugs.