Pain: track genetic

A Canadian team was able to identify a genetic mutation responsible for sensory neuropathy type 2. Today this incurable disease is characterized by loss of pain perception, touch and heat.

Professor Guy Rouleau and his team from the Faculty of Medicine, University of Montreal, have discovered in patients with sensory neuropathy, gene mutations K1F1A. “This result opens the door to a better understanding of this disease,” says Guy Rouleau. “We also take away valuable information about the molecular mechanisms involved in pain perception.”

It is therefore an important discovery. Eventually, a drug could be developed by modulating the interactions between different proteins associated with pain and K1F1A gene.

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