Antihypertensives: detailed review.

Against high blood pressure medicine has 8 family of drugs, collectively known as General of antihypertensives. All promote vasodilatation of the arteries and back to a normal caliber.

Diuretics. They are used in this indication since 1955. Diuretics help to eliminate sodium, discharged with the urine. It is their vasodilator effect exerted at the arterial, which has earned them recognition as the first anti-hypertensive;

Beta-blockers. Indicated for the treatment of angina pectoris, they favor a decrease in the activity of the nervous system. It is their principal mode of action, but they also increase the production of renin, an enzyme necessary for the formation of angiotensin 2. They have long been regarded as leading

Calcium-antagonists or calcium channel blockers. Used for 20 years, these drugs are against some of the mechanisms responsible for arterial vasoconstriction;

Inhibitors of angiotensin converting enzyme. ACE inhibitors inhibit the action of hormones – renin-angiotensin system and involved in the mechanisms of hypertension;

Central antihypertensives. These partially reduced the activity of the central nervous system involved in regulating blood pressure.

Alpha blockers. This class of antihypertensive drugs acting through a mechanism of expansion pressure.

The direct renin inhibitors. As the name implies, drugs that belong to this class of drugs inhibit the production of renin is involved in hypertension.

Receptor antagonists of angiotensin 2. These drugs are the most recently introduced in the treatment of hypertension. They oppose direct action of angiotensin 2, which promotes vasoconstriction;

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